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Changelog

Source: NEWS.md

monolix2rx 0.0.6

CRAN release: 2025-08-29

  • Updated to add types for rstudio completion

  • Defensive drop = FALSE on the imported thetaMat covariance subset so a single surviving parameter is not collapsed to a scalar.

  • Parameters whose off-diagonal covariances are NaN/NA/Inf are now also dropped from the imported thetaMat (previously only the diagonal was checked for NaN/NA, so non-finite covariances could silently propagate into simulations).

  • When every parameter is dropped from the imported thetaMat, the covariance information is now ignored with a warning instead of storing a 0x0 matrix that would break rxSolve() simulations; rxSolve() also warns when nStud > 1 is requested but no thetaMat is available, so uncertainty is never silently omitted.

  • Fixed rxSolve() fallbacks that read dfObs/thetaMat from the wrong location when the values were stored on the model instead of its meta environment.

  • rxSolve() now actually uses the Monolix-style maxSS it reports (number of steady-state doses plus one); previously the computed value was ignored and the literal default 10000L was passed to the solver. The guard also checked missing(maxSS) twice where it meant minSS, so a user-specified minSS no longer gets silently overwritten. Note this can change steady-state simulation results: like Monolix itself, a fixed number of doses is now simulated, so slowly accumulating drugs reproduce Monolix’s (possibly pre-steady-state) concentrations instead of being dosed to full steady state; pass maxSS/minSS explicitly to override.

monolix2rx 0.0.5

CRAN release: 2025-07-15

  • Updated for new solving option in rxode2 4.0 (and depend on the packages)

  • Bug fixes for importing models from lixoftConnectors.

monolix2rx 0.0.4

CRAN release: 2024-11-28

  • Added ignoreline support #22

monolix2rx 0.0.3

CRAN release: 2024-10-24

  • For initial conditions starting with rxCov_ don’t add to ini

monolix2rx 0.0.2

CRAN release: 2024-09-20

  • Remove rxode2parse LinkingTo

  • Add urls for website

  • Remove sentence about the residual specification not always being captured. Right now for ‘Monolix’ it always is.

monolix2rx 0.0.1

CRAN release: 2024-09-20

  • Initial CRAN submission.