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Changelog

Source: NEWS.md

monolix2rx 0.0.7

  • Dropped the re-exports (rxode2(), rxode(), RxODE(), ini(), model(), model<-, rxRename(), rxSolve(), rxUiGet(), logit(), expit(), lotri(), autoplot() and %>%). Load nlmixr2 (or rxode2/magrittr) to get them; this also works around a roxygen2 8.1.0 re-export failure (issue #47, r-lib/roxygen2#1915).

  • monolix2rx(), mlxtran() and mlxTxt() now have dirn to giving the actual directory of the Monolix project, in case the project moved for some reason. This makes it possible to translate project files outside the project directory (#44)

  • The project directory in mlxtran is now absolute.

  • Support the Monolix 2024 file specification file={path='data.csv'} in addition to the older file='data.csv'; the two are equivalent. This applies to the data file in <DATAFILE> [FILEINFO] (and <DATA_FORMATTING> [FILEINFO]) as well as the model file in <MODEL> [LONGITUDINAL] (issue #43).

  • Range-check the input length in all 13 trans_* parser entry-points before narrowing it for dparse()’s int buffer length. A buffer of INT_MAX bytes or more now raises a clean R error instead of handing the parser a truncated (possibly negative) length. This is defensive: every current caller passes an R string, which R already caps at INT_MAX bytes.

monolix2rx 0.0.6

CRAN release: 2025-08-29

  • Updated to add types for rstudio completion

  • Defensive drop = FALSE on the imported thetaMat covariance subset so a single surviving parameter is not collapsed to a scalar.

  • Parameters whose off-diagonal covariances are NaN/NA/Inf are now also dropped from the imported thetaMat (previously only the diagonal was checked for NaN/NA, so non-finite covariances could silently propagate into simulations).

  • When every parameter is dropped from the imported thetaMat, the covariance information is now ignored with a warning instead of storing a 0x0 matrix that would break rxSolve() simulations; rxSolve() also warns when nStud > 1 is requested but no thetaMat is available, so uncertainty is never silently omitted.

  • Fixed rxSolve() fallbacks that read dfObs/thetaMat from the wrong location when the values were stored on the model instead of its meta environment.

  • rxSolve() now actually uses the Monolix-style maxSS it reports (number of steady-state doses plus one); previously the computed value was ignored and the literal default 10000L was passed to the solver. The guard also checked missing(maxSS) twice where it meant minSS, so a user-specified minSS no longer gets silently overwritten. Note this can change steady-state simulation results: like Monolix itself, a fixed number of doses is now simulated, so slowly accumulating drugs reproduce Monolix’s (possibly pre-steady-state) concentrations instead of being dosed to full steady state; pass maxSS/minSS explicitly to override.

monolix2rx 0.0.5

CRAN release: 2025-07-15

  • Updated for new solving option in rxode2 4.0 (and depend on the packages)

  • Bug fixes for importing models from lixoftConnectors.

monolix2rx 0.0.4

CRAN release: 2024-11-28

  • Added ignoreline support #22

monolix2rx 0.0.3

CRAN release: 2024-10-24

  • For initial conditions starting with rxCov_ don’t add to ini

monolix2rx 0.0.2

CRAN release: 2024-09-20

  • Remove rxode2parse LinkingTo

  • Add urls for website

  • Remove sentence about the residual specification not always being captured. Right now for ‘Monolix’ it always is.

monolix2rx 0.0.1

CRAN release: 2024-09-20

  • Initial CRAN submission.