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  • Add Carlsson Petri (2021) liraglutide PK model

Version 0.2.0

CRAN release: 2023-03-29

  • Work with the new rxode2 version 2.0.12 model() and ini() assignment methods.
  • Therapeutic-area specific models have begun being added.
  • Models can now give the user some additional information load via the message meta-data.
  • Models can now be in different directories. The change is for ease of maintaining the library, it is not a change that affects users.
  • A regression where addEta() did not change the parameter, related to a change in rxode2, was fixed.
  • addEta() detects where to add etas more robustly when covariates are on the parameter.

Models added

  • Add Davda (2014) mAb consensus model
  • Add Liu (2017) time-dependent clearance model based on nivolumab
  • Add Kovalenko (2020) dupilumab PK model
  • Add Soehoel (2022) tralokinumab PK model
  • Add Zhu (2017) lebrikizumab PK model

Version 0.1.0

CRAN release: 2022-10-31

  • Initial version