This is a example dataset originally created to show how similar
mrgsolve and NONMEM were (See ).
Format
A data frame with 7,157 rows and 15 columns
- id
NONMEM id
- time
NONMEM time
- cp
NONMEM cp output from 7.4.3
- cmt
cmt specification 1=depot, 2=central
- amt
Nonmem dose
- evid
NONMEM Event ID
- ii
Interdose Interval
- ss
Steady state flag
- addl
Individual Clearance
- rate
Rate of the infusion
- lagt
Lag time
- bioav
Bioavailability
- rat2
Modeled rate when
mode== 1- dur2
Duration when
mode== 2- mode
Mode = 0 is no modification, modeled rate when mode=1 and modeled duration when mode=2
Details
The original dataset was created by Kyle Baron and is composed of
id<100 the id>100 are modifications by Matthew Fidler to
benchmark steady state infusions with lag times and other uncommon
features.
Note that rxode2/nlmixr2 will not always match these behaviors
by default, we choose behaviors that we believe make sense. There
are options to make rxode2/nlmixr2 behave more like NONMEM.
However behaviors we believe are wrong we do not support.
See also
Other nlmixr2 datasets:
Bolus_1CPTMM,
Bolus_1CPT,
Bolus_2CPTMM,
Bolus_2CPT,
Infusion_1CPTMM,
Infusion_1CPT,
Infusion_2CPTMM,
Infusion_2CPT,
Oral_1CPTMM,
Oral_1CPT,
Oral_2CPTMM,
Oral_2CPT,
Wang2007,
mavoglurant,
nimoData,
pheno_sd,
rats,
theo_md,
theo_sd,
warfarin,
wbcSim