Output table/data.frame options

Usage

tableControl(
  npde = NULL,
  cwres = NULL,
  nsim = 300,
  ties = TRUE,
  censMethod = c("truncated-normal", "cdf", "ipred", "pred", "epred", "omit"),
  seed = 1009,
  cholSEtol = (.Machine$double.eps)^(1/3),
  state = TRUE,
  lhs = TRUE,
  eta = TRUE,
  covariates = TRUE,
  addDosing = FALSE,
  subsetNonmem = TRUE,
  cores = NULL,
  keep = NULL,
  drop = NULL
)

Arguments

npde

When TRUE, request npde regardless of the algorithm used.

cwres

When TRUE, request CWRES and FOCEi likelihood regardless of the algorithm used.

nsim

represents the number of simulations. For rxode2, if you supply single subject event tables (created with [eventTable()])

ties

When `TRUE` jitter prediction-discrepancy points to discourage ties in cdf.

censMethod

Handle censoring method:

- `"truncated-normal"` Simulates from a truncated normal distribution under the assumption of the model and censoring.

- `"cdf"` Use the cdf-method for censoring with npde and use this for any other residuals (`cwres` etc)

- `"omit"` omit the residuals for censoring

seed

an object specifying if and how the random number generator should be initialized

cholSEtol

The tolerance for the `rxode2::choleSE` function

state

is a Boolean indicating if `state` values will be included (default `TRUE`)

lhs

is a Boolean indicating if remaining `lhs` values will be included (default `TRUE`)

eta

is a Boolean indicating if `eta` values will be included (default `TRUE`)

covariates

is a Boolean indicating if covariates will be included (default `TRUE`)

addDosing

Boolean indicating if the solve should add rxode2 EVID and related columns. This will also include dosing information and estimates at the doses. Be default, rxode2 only includes estimates at the observations. (default FALSE). When addDosing is NULL, only include EVID=0 on solve and exclude any model-times or EVID=2. If addDosing is NA the classic rxode2 EVID events are returned. When addDosing is TRUE add the event information in NONMEM-style format; If subsetNonmem=FALSE rxode2 will also include extra event types (EVID) for ending infusion and modeled times:

EVID=-1 when the modeled rate infusions are turned off (matches rate=-1)
EVID=-2 When the modeled duration infusions are turned off (matches rate=-2)
EVID=-10 When the specified rate infusions are turned off (matches rate>0)
EVID=-20 When the specified dur infusions are turned off (matches dur>0)
EVID=101,102,103,... Modeled time where 101 is the first model time, 102 is the second etc.

subsetNonmem

subset to NONMEM compatible EVIDs only. By default TRUE.

cores

Number of cores used in parallel ODE solving. This is equivalent to calling setRxThreads()

keep

is the keep sent to the table

drop

is the dropped variables sent to the table

Value

A list of table options for nlmixr2

Details

If you ever want to add CWRES/FOCEi objective function you can use the addCwres

If you ever want to add NPDE/EPRED columns you can use the addNpde

Author

Matthew L. Fidler