Skip to contents

All functions

as.nlmixr2() as.nlmixr()
Convert an object to a nlmixr2 fit object
babel.poped.database()
Expand a babelmixr2 PopED database
babelBpopIdx()
Get the bpop_idx by variable name for a poped database created by babelmixr2
bblDatToMonolix() bblDatToNonmem() bblDatToRxode() bblDatToMrgsolve() bblDatToPknca()
Convert nlmixr2-compatible data to other formats (if possible)
.nlmerNlmerFun()
Surrogate gradient function for lme4::nlmer
.setupPopEDdatabase()
Setup the poped database
fmeMcmcControl()
Control for fmeMcmc estimation method in nlmixr2
getStandardColNames()
Determine standardized rxode2 column names from data
modelUnitConversion()
Unit conversion for pharmacokinetic models
monolixControl()
Monolix Controller for nlmixr2
nlmixr2Est(<nlmer>)
nlmixr2 estimation using lme4::nlmer
nlmixr2Est(<pknca>)
Estimate starting parameters using PKNCA
nlmixr2NlmerControl() nlmerControl()
Control for nlmer estimation method in nlmixr2
nonmemControl()
NONMEM estimation control
pkncaControl()
PKNCA estimation control
popedControl()
Control for a PopED design task
popedGetMultipleEndpointModelingTimes() popedMultipleEndpointIndexDataFrame()
Get Multiple Endpoint Modeling Times
popedMultipleEndpointResetTimeIndex()
Reset the Global Time Indexer for Multiple Endpoint Modeling
pseudoOptimControl()
Control for fmeMcmc estimation method in nlmixr2
rxToMonolix()
Convert RxODE syntax to monolix syntax
rxToNonmem()
Convert RxODE syntax to NONMEM syntax
rxUiGet(<loadPruneNlmer>)
Load pruned nlmer model into symengine (no sensitivity promotion)
rxUiGet(<loadPruneNlmerSens>)
Load pruned nlmer model into symengine (with sensitivity promotion)
rxUiGet(<nlmerEnv>)
Full nlmer symengine environment with sensitivities
rxUiGet(<nlmerFormula>)
Build the full 3-part nlmer formula
rxUiGet(<nlmerHdTheta>)
Compute d(f)/d(THETA[i]) for all nlmer parameters
rxUiGet(<nlmerModel0>)
nlmer base model (saem-dropped etas, THETA[i] prefix, nlme error lines)
rxUiGet(<nlmerParams>)
params() string for the nlmer THETA[i]-indexed model
rxUiGet(<nlmerRandomFormula>)
Build the random-effects part (part 3) of the nlmer 3-part formula
rxUiGet(<nlmerSensModel>)
Compiled nlmer sensitivity model (prediction + gradients)
rxUiGet(<nlmerStart>)
Starting values for nlmer fixed effects
rxUiGet(<nlmerThetaS>)
Compute d(state)/d(THETA[i]) sensitivities for nlmer
rxUiGet(<nlmerThetas>)
Get the structural params to estimate for nlmer (= saemParamsToEstimate)
saemixControl()
Control for saemix estimation method in nlmixr2
simplifyUnit()
Simplify units by removing repeated units from the numerator and denominator